China launches inhaled Covid vaccine

Chinese regulators approved the vaccine for use as a booster in September

Author: Jon BurkePublished 26th Oct 2022

The Chinese city of Shanghai has started administering an inhalable Covid-19 vaccine, in what appears to be a world first.

The vaccine, a mist that is sucked in through the mouth, is being offered free of charge as a booster dose for previously vaccinated individuals.

This is according to an announcement, posted on an official city social media account.

Needle-free vaccines may persuade people who do not like getting a shot to get vaccinated, as well as help expand inoculation in poor countries because they are easier to administer.

China does not have vaccine mandates, but wants more people to get booster shots before it relaxes strict pandemic restrictions that are holding back the economy and increasingly out of sync with the rest of the world.

A video posted by an online Chinese state media outlet showed people at a community health centre putting the short nozzle of a translucent white cup in their mouths.

Accompanying text said that, after slowly inhaling, one individual held his breath for five seconds, with the entire procedure completed in 20 seconds.

'It tasted a bit sweet'

"It was like drinking a cup of milk tea," one Shanghai resident said in the video. "When I breathed it in, it tasted a bit sweet."

A vaccine taken orally could also fend off the virus before it reaches the rest of the respiratory system, though that would depend in part on the size of the droplets, one expert said.

Larger droplets would train defences in parts of the mouth and throat, while smaller ones would travel further into the body, said Dr Vineeta Bal, an immunologist in India.

Chinese regulators approved the vaccine for use as a booster in September. It was developed by Chinese biopharmaceutical company Cansino Biologics Inc as an aerosol version of the same company's one-shot adenovirus vaccine, which uses a relatively harmless cold virus.

Cansino has said the inhaled vaccine has completed clinical trials in China, Hungary, Pakistan, Malaysia, Argentina and Mexico.

Regulators in India have approved a nasal vaccine, another needle-free approach, but it has yet to be rolled out. The vaccine, developed in the US and licensed to Indian vaccine-maker Bharat Biotech, is squirted in the nose.

About a dozen nasal vaccines are being tested globally, according to the World Health Organisation.

What is the Pfizer-BioNTech vaccine?

The Pfizer-BioNTech vaccine was approved for use in the UK on 2 December 2020. Britain was the first country in the world to approve the jab, which offers up to 95% protection against Covid-19. Pfizer is an American pharmaceutical firm while BioNTech is a German biotechnology company. The vaccine is very delicate and has to be stored at -70 degrees, limiting the number of sites that can administer the jab.

What is the Oxford/AstraZeneca vaccine?

A vaccine developed by Oxford University and pharmaceutical company AstraZeneca became the second vaccine approved for UK use on 30 December 2020. This vaccine was considered "the way out" of the pandemic in the UK, thanks to the fact it is easier to store than the Pfizer jab, making it well equipped for mass roll out. GPs and vaccination centres across the country began administering the jab in early January 2021. Under 30's in the U.K. were given the option to choose a different vaccine to this due to small risks of very rare blood clots. Instead, under-30s would typically choose the Pfizer jab or later, the moderna jab.

What is the Moderna vaccine?

The third vaccine approved for UK use on 8 January 2021 was developed by American firm Moderna. 24-year-old Elle Taylor from Wales became the first person in the UK to receive the Moderna jab in April. The Moderna vaccine is similar to the Pfizer jab in how it works but is even easier to roll out as it can be stored at -20 degrees rather than -70.

What is the Johnson & Johnson vaccine

The fourth vaccine to be be approved in the UK was Johnson & Johnson's vaccine, released under the name Janssen. Notably, It is also the first single shot vaccine in use during this vaccine rollout.

Who was the first person to receive the Pfizer vaccine?

90-year-old Margaret Keenan became the first patient in the world to be vaccinated against Covid-19 outside a clinical trial. She received her jab on 8 December 2020 at Coventry's University Hospital. Mrs Keenan, who lives in Coventry, became somewhat of a fashion influencer after the charity t-shirt she wore to her vaccination appointment sold out. Profits went towards buying Christmas presents for hospital patients. The grandmother advised everyone who was offered the vaccine to take it, saying "If I can have it at 90, then you can have it too."

Who was the first person to receive the Oxford vaccine?

Meanwhile, Brian Pinker from Oxford was first to receive the AstraZeneca jab outside of a clinical trial at the age of 82. Mr Pinker, who was vaccinated on 4 January 2021, praised the medical teams administering the vaccine, saying it would allow him to "really look forward" to celebrating his 48th wedding anniversary with wife Shirley later on in the year.

When will I receive the vaccine?

Vaccines were offered according to vulnerability levels. First to be offered the jab were people in care homes and their carers, followed by those over 80 and health and social care workers. People aged 65 and above were next on the priority list and then high-risk adults under the age of 65 followed by moderate risk adults under 65. The vaccine was then rolled out by age group.

How will I know when it's my turn to get vaccinated?

When it is your turn to receive the vaccination, you will be informed by the NHS. You should only attend vaccination sites if you have been told to do so. Vaccines are provided for free by the NHS and they will never ask for bank details. Find out more about vaccine scams here.

What is a vaccine passport?

The Government debate the idea of a vaccine passport as proof of full vaccination required to enter venues like nightclubs. Health Secretary Sajid Javid later "ditched" the idea and ensured clubbers that they no longer need to be double jabbed by the end of September 2021 to get into Nightclubs or big events.

Do I need a booster jab?

Pfizer/BioNTech booster jabs are rolled out as part of the Government's winter covid plan. Shots can be given to people aged 50 and over, those in care homes and frontline health and social care workers. All those who are clinically extremely vulnerable and anyone aged 16 to 65 in an at-risk group for Covid will also be eligible for a jab. There must be at least 6 months between a 2nd vaccine dose and a booster jab.
Oxford jab scientist Sarah Gilbert says booster jabs are "not needed for all" and that they should instead go to countries with low vaccination rates.

Will children be vaccinated?

The government have also made vaccines available to children aged between 12-15 as part of the country's winter Covid plan.

What about five to 11-year-olds getting vaccinated?

All 5 to 11-year-olds in England can now receive a coronavirus jab, following advice from the JCVI and the same decision being made in Scotland and Wales. Northern Ireland is also expanding their vaccination programme to include the 5-11 age range. It means almost six million children in the UK will be offered the Covid-19 vaccination.

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